Dioctyl adipate is one of the most important esters in the world that has various uses. This material is used in various industries; It is used for the production of building insulation of various types of refractory materials as well as durable plastics of dioctyl adipate. It can also be used to make cosmetics. In 1981, the FDA approved the substance for use in the production of cosmetics as well as bath products. Then, it was used to make soap and shampoo as well as cosmetics.

What is Dioctyl Adipate? Is the use of this substance harmful?

Dioctyl adipate is an important ester in global industries that has various applications. This material is used to produce a variety of durable plastics and is also used to insulate buildings. It is interesting to know that this substance is also used as an industrial solvent. Another application of DOA is PVC softener. This material is used to produce a variety of auto parts as well as aircraft parts.

Dioctyl adipate is also known by the acronym DOA in the industry. This substance is confused with DOP or dioctyl phthalate! Because DOP is also composed of dioctyl but contains phthalates. The raw material for the production of DOP is phthalic anhydride, which after combustion produces toxic fumes.

DOA is used in various industries due to its unique and appropriate properties. This material is very resistant to heat and is used to produce a variety of durable plastics such as polystyrene GPPS and polystyrene HIPS.

Given the numerous applications of this substance in the industry, it is very important to review DOA Hazards. In 1981, the FDA declared that the use of DOA was not harmful to human health. The FDA conducted these studies on humans and various animals and authorized the use of soaps and dioctyl adipate shampoos.

DOA shampoos

DOA shampoos

After 1981, in 1987, the use of cosmetics made from dioctyl adipate became popular. Therefore, according to DOA Hazards, this substance can be used by humans. It should be noted that various experiments have been performed on DOA Hazards in which animals have been studied. In the first and second articles on DOA Hazards, we looked at different experiments. In this article, we want to see other experiments performed on animals.

Review of DOA Hazards in various studies

In general, the use of DOA is not harmful to human health; If this substance was harmful, it would not be used in food packaging! This material is produced in different ways and certain standards are set for its production and use.

Due to temperature changes in different environments, Iran DOA production is done by considering very high temperatures. This material heats up to 200 ° C and does not lose its physical and chemical properties! It is only converted to pure carbon and used to make graphite.

It is interesting to note that chemicals often produce toxic gases after burning. But DOA does not produce toxic fumes after burning and turns into pure and useful graphite. This material is used in various industries; Therefore, DOA Hazards are not registered for the health of consumers and workers of the dioctyl adipate product line.

1. Investigation of the effect of dioctyl adipate on the mucous membrane

In the experiments, six female white rabbits were used; In these experiments, dioctyl adipate was used and injected intravenously. This substance was injected into rabbits at a dose of 0.1 ml. This DOA Hazards test lasted 7 days. It is interesting to know that after recording the results, no bad effects were recorded on rabbits.

2. Use DOA to monitor weight gain in animals

monitor weight gain in animals

monitor weight gain in animals

In other experiments, a population of 60 mice was examined and these 60 mice were divided into 6 groups. Each of these groups was given different doses of DOA orally. These doses are: 0, 1600, 3100, 6300, 12500 and 25000 PPM. In general, it takes a long time to add these doses to the diet of mice. These experiments lasted 91 days! After 91 days, interesting results were recorded to determine DOA Hazards!

These results showed that this substance causes weight gain in groups 2 and 3. But after 91 days, the weight of the mice is constant and no weight gain is observed. In group 4, weight gain was observed for only 13 days and after that, the weight of mice was fixed. In groups 5 and 6, the weight of mice was almost constant! This shows that DOA did not cause much harm to the health of mice.

3. Check DOA Hazards to determine damage to the nervous system

In other experiments, DOA was used to determine central nervous system damage. In these experiments, mice were divided into 3 groups, and groups 1, 2, and 3 were given 0.4, 1, and 2 g of DOA, respectively. It was given orally to mice.

These studies lasted more than 6 months! DOA in these experiments did not alter the enzyme system of the mice but did alter the level of blood components as well as hepatic problems. After 10 months, these experiments were completed and it was observed that very little effect of this substance remained on the nervous system of mice; So a DOA Hazards study shows that this substance is not harmful to brain health!

4. Determine pathogenicity for DOA

In other experiments, the substance was injected into different groups of bacteria at different doses. In this experiment, it was recorded that this substance can grow in the body of bacteria and cause liver problems after entering the human body.

Of course, this review was not very real! Because the bacteria used in this test rarely enter the human body and cause disease.

5. DOA Hazards test to determine carcinogenicity in animals

DOA Hazards test to determine carcinogenicity

DOA Hazards test to determine carcinogenicity

In other experiments, the substance was used for a population of 100 mice! It was given to mice at various doses of 12,000 to 25,000 ppm. It was then determined that this experiment would take 103 weeks. After this period, surveys were collected and data were displayed.

The results showed that the substance did not have a significant effect on the health of mice in terms of cancer. No carcinogenicity was observed in the two groups of mice. In the other two groups, very few effects of liver damage were observed. So DOA Hazards are not dangerous in terms of carcinogenesis either!

A summary of the DOA Hazards review and its studies

In this article from PETROPROVIDERS, we reviewed DOA Hazards. This material has various applications around the world and it is used to produce a variety of durable plastic products. It is interesting to know that this material is used for insulating buildings as well as softening PVC. The production of Iran dioctyl adipate and the use of DOA for the production of refractory materials are also widely used.

DOA Hazards study shows that this substance has very minor damage to animals. This substance is not carcinogenic and does not cause pathogenesis. In addition, its use does not have a bad effect on the nervous system. It does not have a bad effect on the mucous membranes of the body; But it was shown that this substance in low doses, increases the weight of mice!

What do you think of DOA Hazards? Does using this substance cause carcinogenesis? Why do you think the FDA has authorized the use of this chemical? Do you see dioctyl adipate in everyday life? In the comments section, you can share your questions and comments with our experts. In addition, you can contact us to buy the best IRAN DOP.


Is dioctyl adipate carcinogenic?

No! Studies have shown that the use of this substance does not cause cancer in humans.

Is using DOA dangerous?

By examining DOA Hazards, we conclude that this substance is not harmful to human health. In addition, the FDA has approved its use!

What is Dioctyl Adipate?

Dioctyl adipate is a widely used ester used in various industries. This material is used to produce a variety of durable products.

What are the uses of Dioctyl Adipate?

Production of refractory materials, building insulation, auto parts, aircraft parts, heat-resistant materials, PVC softeners, industrial solvents.

What can we do to buy the best DOA?

To buy Iran Dioctyl Adipate, contact our experts.